Safety data sheet monopropylene glycol mpg section 1. Propylene glycol is used as a drench in the treatment of ketosis. Never give anything by mouth to an unconscious person. An expert panel convened by the ntps center for the evaluation of risks to human reproduction concluded 23 that developmental and reproductive risks stemming from exposure to the chemicals propylene glycol and ethylene glycol are negligible.
Ethylene glycol industrialethylene glycol meglobal glycol solv ethylene glycol, section 4. Material safety data sheet propylene glycol industrial grade august 17, 2011 page 3 of 6 handling and storage general. Identification of the substance preparation and of the company undertaking product identifier. Firstaid measures description of first aid measures do not induce vomiting. Antifreeze breaks down over time and forms acids, which corrode the vehicles cooling system. Safety data sheet monopropylene glycol page 1 issued. Call a physician or poison control center immediately. Identification of the substancemixture and of the companyundertaking date issued 04. Identification of the substancemixture and of the companyundertaking 1.
Propylene glycols are hygroscopic liquids and efficient humectants. Pg60ml, pg120ml, pg250ml, pg500ml, pg1gal, pg5gal synonyms. Propylene glycol is included in pediculicide drug products. Identification product identifier propylene glycol 40% version. Safety data sheet ethylene glycol 100% inhibited page 3 of 10. In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. It has low vapor pressures at room temperature and, therefore, low potential for significant inhalation exposure. The propylene glycol family of chemical compounds consists of monopropylene glycol pg, dipropylene glycol dpg, and tripropylene glycol tpg. Propylene glycol usp the generation of waste should be avoided or minimized wherever possible. Ethylene glycol industrialethylene glycol meglobalglycolsolv ethylene glycol, section 4. Propylene glycol usp proper handling page 2 of 3 if good hygienic practices are followed and the recommended materials of construction are used, the handling of propylene glycol usp should be no problem.
Ethylene glycol and propylene glycol have similar physical properties and uses. Boiling point of aqueous propylene glycol solutions. Product identifier product name monopropylene glycol mpg chemical name 1,2propylenglykol reach reg no. Dipropylene glycol, industrial grade dpg, with almost identical properties, is frequently used in resins and cleaner formulations where low odor is. Use extinguishing measures that are appropriate to local circumstances and the surrounding environment. All these documents, with focus on pharmaceutical applications may serve as additional. First aid measures general advice consult a physician. Exposures to propylene glycol having no adverse effects on the mother should have no effect on the fetus. Antifreeze is used as an engine coolant and commonly consists of ethylene glycol or propylene glycol. Page 1 of 5 january 18, 20 continued on next p age section 1.
Propylene glycol c3h8o2 cid 1030 structure, chemical names, physical and. Propylene glycol pg uspep is a pharmacopeiaspecificationsgrade excipient of monopropylene glycol pg or mpg with a specified purity greater than 99. Propylene glycol, propan 1, 2 diol, dowcal 20, dowcal n, 1, 2 propylene glycol care. Propylene glycol rarely causes toxic effects, and then only under very unusual. Common name 1,3butylene glycol formula c 4 h 10 o 2 cas number 107880 component cas number concentration 1,3butylene glycol 107880 99. Nevertheless osmolar gap increases with increase in propylene glycol concentration and in general the correlation is strongest as lorazepam. Pg uspep is tested for compliance with the current united states pharmacopeia usp. Glycol is metabolized, metabolic acidosis and further central nervous system depression convulsions, muscle weakness develop. Serious intoxication may develop to coma associated with hypotonia, hyporeflexia, and less commonly seizures, and meningismus. As such, they attract and hold water when exposed to the environment. Nsf international nonfood compounds registration program. Dow propylene glycol uspep general description propylene glycol uspep pg uspep, referring to the united states and european pharmacopoeias, is a highpurity grade of monopropylene glycol for use in pharmaceutical, food, cosmetic, personal care, flavor and fragrance, plus a variety of other applications.
Drug products containing certain active ingredients offered over the counter otc for certain uses. Product identifier product name mono propylene glycol usp product number 31055 cas number 57556 ec number 2003380 1. Heating may cause a violent combustion or explosion producing toxic fumes nitrogen oxides. Pll, a global leader in filtration, separation and purification, today announced it has completed the acquisition of filter specialists, inc. Propylene glycol used as an excipient european medicines agency. Immediately flush eyes with excess water for 15 minutes, lifting lower and upper eyelids occasionally. Box 4980 the woodlands, tx 77387 telephone numbers transportationemergency chemtrec. Propylene glycols are sensitive to oxidizing agents, e. On burning will emit toxic fumes, including those of oxides of carbon. Chemical of the day todays chemical propylene glycol.
Revision bulletin 2 propylene official february 1, 2010 ature is 250, and the column temperature is programmed at a rateprocedureinject a suitable volume, typically about 10 l, of of 5 per minute from 120 to 200, and helium is used as the car propylene glycol into a suitable gas chromatograph, and record the. Dow propylene glycol is a viscous, colorless, odorless liquid. In order to access the atsdr toxicological profiles pdf files below, you must have adobe acrobat reader. Just remember that it should be handled as though it were a food. Propylene glycol safety data sheet according to federal register vol. Physical properties units propylene glycol dipropylene glycol tripropylene glycol density gcm 3, 77f25c 1. Propylene glycol is a highpurity material, which must be handled with special precautions to avoid contamination. Safety data sheet page 1 of 6 may 11, 2017 section 1. Mono propylene glycol usp this sds is not mandated under reach regulation ec no 19072006 and is provided for information only.
Technical data propylene glycol specific gravity of aqueous propylene glycol solutions gravity chart specific gravity of aqueous propylene glycol solutions 1. Propylene glycol provides the rumen the precursors for the animal to create its own glucose, due to its fate in the rumen environment. Reproductive effects this substance is not expected to be a reproductive toxicant. Handle in accordance with good industrial hygiene and safety practice. Propylene glycol glycol, 1,2 propandiol 57556 99 100% 2017. First aid measures always seek professional medical attention after first aid measures are provided. Dow propylene glycol is used as a raw material for the manufacture of other chemicals and as an ingredient in product formulations. Chemtrec 8004249300 outside usa 7035273887 1216 6th ave n kent wa 98032 phone. Identification of the substance monopropylene glycol cas number 57556 alternative names 1. The subject of the current petition is a request for the approval of propylene glycol to the national list for medical use in organic livestock. Propylene glycol 000057556 95% na dipotassium phosphate 007758114 sheet. May also decompose explosively from shock, friction or from a buildup of electrostatic charge that sparks suddenly to ground. Download printerfriendly version adobe pdf file pdf 496. Propylene glycol is a 3carbon compound derived from propylene which has applications in both industry and medicine.
Propylene glycol used in animal drugs, feeds, and related products is generally recognized as safe except in cat food when used in accordance with good manufacturing or feeding practice. Propylene glycol,us nsn 6505006873667 niin 006873667 procurement. Special hazards or target organ effects are given as a generic warning, substance specific data is not available. Show this safety data sheet to the doctor in attendance. Special hazards arising from the substance or mixture fire hazard. Dispose of surplus and nonrecyclable products via a. Under ordinary conditions, mild steel is a satisfactory material of construction. In animal studies, propylene glycol has been shown not to interfere with reproduction. Safety data sheet propylene glycol usp wizard labs. Ethylene glycol is a clear, colorless, odorless, sweettasting liquid. National regulations propylene glycol listed on piccs philippines inventory of chemicals and chemical substances. Show this safety data sheet to the doctor in advance. Only use in wellventilated areas wash thoroughly after handling refer to personal protection section use the information in this data sheet as input to a risk. This material and its container must be disposed of in a safe way.
Dipropylene glycol, fragrance grade is commonly used as a carrier for fragrances. An alternative, albeit a temporary bandaid type fix and one that acts directly on the bloodstreams glucose level is intravenous dextrose or glucose allowed. No repeated inhalation exposure studies are available for tripropylene glycol or dipropylene glycol. Chemical product and company identification product name. During its use, antifreeze may become contaminated with traces of fuel, metal particles, and grit. Invalid emails will appear to work, but in reality we will not receive them. Have victim rinse mouth with water, then give one to two glasses of water to drink. Material safety data sheet validation date product and company identification 1. Nsf international nonfood compounds registration program sandra kupperblatt dow chemical company, the united states midland, mi 48674 february 12, 2004 re. Remove contaminated, soaked clothing immediately and dispose of safely. Material safety data sheet page 1 of 2 propylene glycol. Safety data sheet 1,3butylene glycol date prepared. Fire fighters to wear selfcontained breathing apparatus and suitable protective clothing if risk of exposure to vapour or products of combustion.
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